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LTB4DH Antibody - N-terminal region : HRP (ARP54865_P050-HRP)

Product Specifications

Gene Name

Prostaglandin reductase 1

Gene Aliases

PGR1, DIG-1, ZADH3, LTB4DH

Gene ID

22949

Swiss Prot

A8K0N2

Accession Number

NP_036344

Host

Rabbit

Reactivity

Human, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LTB4DH

Target

LTB4DH functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. It has no activity towards PGE1, PGE2 and PGE2-alpha. LTB4DH catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.

Partner Proteins

PRDX5; PEBP1; ATP6V1A; UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Guinea Pig: 83%; Horse: 83%; Human: 93%; Rabbit: 83%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Chou, W.L., (2007) J. Biol. Chem. 282 (25), 18162-18172

Shipping Conditions

Wet Ice

Product Datasheet

Anti-PTGR1 (ARP54865_P050-HRP) antibody

Protein Length

329

NCBI Gene Symbol

PTGR1

NCBI GB Accession Number

PTGR1

Host or Source

Rabbit

Protein Name

Prostaglandin reductase 1

Nucleotide Accession Number

NM_012212

Peptide Sequence

VRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVLLEALFLTVDPYMR

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