LTB4DH Antibody - N-terminal region : Biotin (ARP54865_P050-Biotin)
Product Specifications
Gene Name
Prostaglandin reductase 1
Gene Aliases
PGR1, DIG-1, ZADH3, LTB4DH
Gene ID
22949
Swiss Prot
A8K0N2
Accession Number
NP_036344
Host
Rabbit
Reactivity
Human, Rat, Cow, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human LTB4DH
Target
LTB4DH functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. It has no activity towards PGE1, PGE2 and PGE2-alpha. LTB4DH catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.
Partner Proteins
PRDX5; PEBP1; ATP6V1A; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Guinea Pig: 83%; Horse: 83%; Human: 93%; Rabbit: 83%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
References & Citations
Chou, W.L., (2007) J. Biol. Chem. 282 (25), 18162-18172
Shipping Conditions
Wet Ice
Protein Length
329
NCBI Gene Symbol
PTGR1
NCBI GB Accession Number
PTGR1
Host or Source
Rabbit
Protein Name
Prostaglandin reductase 1
Nucleotide Accession Number
NM_012212
Peptide Sequence
VRTKTWTLKKHFVGYPTNSDFELKTSELPPLKNGEVLLEALFLTVDPYMR
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