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CDC42EP4 Antibody - N-terminal region : Biotin (ARP54839_P050-Biotin)

Product Specifications

Gene Name

CDC42 effector protein (Rho GTPase binding) 4

Gene Aliases

CEP4, BORG4, KAIA1777

Gene ID

23580

Swiss Prot

Q9H3Q1

Accession Number

NP_036253

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CDC42EP4

Target

CDC42EP4 is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. The protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, the protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

Partner Proteins

FAM9B; SRPK2; UBC; VCP; APP; LNX1; ELAVL1; CDC42; POLR3H; WDR6; RHOQ; TGFBR1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CDC42EP4 is strongly supported by BioGPS gene expression data to be expressed in HeLa There is BioGPS gene expression data showing that CDC42EP4 is expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

356

NCBI Gene Symbol

CDC42EP4

NCBI GB Accession Number

CDC42EP4

Host or Source

Rabbit

Protein Name

Cdc42 effector protein 4

Nucleotide Accession Number

NM_012121

Peptide Sequence

SSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLPQ

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