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APPL1 Antibody - middle region : Biotin (ARP54834_P050-Biotin)

Product Specifications

Gene Name

Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Gene Aliases

APPL, MODY14, DIP13alpha

Gene ID

26060

Swiss Prot

Q9UKG1

Accession Number

NP_036228

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human APPL1

Target

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A

Partner Proteins

RHEBL1; UBE2O; APPL2; APPL1; FARS2; MEOX1; MAGEA9; UBC; KIAA1468; CLUH; TTC4; TRAF6; ADIPOR1; HDAC5; HDAC3; HDAC2; PIK3R1; AR; AKT1; CMTM4; PLEKHF2; KXD1; DPYSL5; EGFR; RAB21; VCP; RAB5A; AKT2; ADIPOR2; FSHR; ELAVL1; MTA2; RBBP7; RUVBL2; RBBP4; HDAC1; TRA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 75%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

80kDa

References & Citations

McCrea, H.J., (2008) Biochem. Biophys. Res. Commun. 369 (2), 493-499

Shipping Conditions

Wet Ice

Protein Length

709

NCBI Gene Symbol

APPL1

NCBI GB Accession Number

APPL1

Host or Source

Rabbit

Protein Name

DCC-interacting protein 13-alpha

Nucleotide Accession Number

NM_012096

Peptide Sequence

GQAKAFGQGGRRTNPFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDD

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