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PRDX5 Antibody - middle region : Biotin (ARP54832_P050-Biotin)

Product Specifications

Gene Name

Peroxiredoxin 5

Gene Aliases

PLP, ACR1, B166, PRXV, PMP20, PRDX6, prx-V, SBBI10, AOEB166, HEL-S-55

Gene ID

25824

Swiss Prot

B7ZVW3

Accession Number

NP_857635

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Goat, Guinea Pig, Horse, Pig, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PRDX5

Target

PRDX5 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

UBC; MDM2; WWOX; ATF2; PEX5; TOMM40; PRDX6; STAM; SUMO1; UBE2B; UBE2A; PRDX2; VAMP2; SOD1; RPS12; RAD23B; PTMS; PRDX1; MDH1; IGBP1; APP; ZFYVE19; PSRC1; GINS4; UBAP2; PTPN23; PTGR1; PARK7; IFT27; SEC24A; SSSCA1; ICT1; BABAM1; CCDC90B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Goat: 79%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rat: 93%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

References & Citations

Trujillo, M., (2007) Arch. Biochem. Biophys. 467 (1), 95-106

Shipping Conditions

Wet Ice

Protein Length

125

NCBI Gene Symbol

PRDX5

NCBI GB Accession Number

PRDX5

Host or Source

Rabbit

Protein Name

Peroxiredoxin 5 EMBL AAI71733.1

Nucleotide Accession Number

NM_181652

Peptide Sequence

TDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNI

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