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CCT5 Antibody - C-terminal region : Biotin (ARP54826_P050-Biotin)

Product Specifications

Gene Name

Chaperonin containing TCP1, subunit 5 (epsilon)

Gene Aliases

CCTE, HEL-S-69, PNAS-102, CCT-epsilon, TCP-1-epsilon

Gene ID

22948

Swiss Prot

P48643

Accession Number

NP_036205

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CCT5

Target

CCT5 is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

SSSCA1; HUWE1; UBC; TP53; FUS; TUBG1; SUMO2; SUMO3; LGALS3BP; CDC20; NEDD1; MDM2; RNF2; CCT8; CCT2; CCT7; FBXO6; UBD; TERT; FBXW4; CDK9; CDK5; HDAC6; HDAC3; ILK; CDK2; PAN2; FAM86B2; PEX14; NOS2; ITGA4; FN1; ATF2; METTL21B; VCAM1; VCP; PACRG; AHCYL1; CCT6

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CCT5 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Lam, C.Y., (er) Invest. Ophthalmol. Vis. Sci. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

541

NCBI Gene Symbol

CCT5

NCBI GB Accession Number

CCT5

Host or Source

Rabbit

Protein Name

T-complex protein 1 subunit epsilon

Nucleotide Accession Number

NM_012073

Peptide Sequence

DCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE

Subunit

Epsilon

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