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PHGDH Antibody - middle region : FITC (ARP54801_P050-FITC)

Selected Variant

ARP54801_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Phosphoglycerate dehydrogenase

Gene Aliases

NLS, PDG, PGD, NLS1, PGAD, PGDH, SERA, 3PGDH, 3-PGDH, PHGDHD, HEL-S-113

Gene ID

26227

Swiss Prot

O43175

Accession Number

NP_006614

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PHGDH

Target

3-Phosphoglycerate dehydrogenase (PHGDH) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.[supplied by OMIM].

Partner Proteins

HUWE1; UBC; FUS; SUMO2; ITSN1; ROM1; RPAP3; EPN1; SUMO1; NEDD8; MDM2; SUZ12; RNF2; EZH2; BMI1; FBXO6; TARDBP; EGFR; UBD; CLN5; CLN3; CDK2; PIAS4; FN1; TRAF3IP1; ECT2; MDC1; UQCC3; VASN; TRIM55; SMU1; TRA2A; ADNP; NCSTN; U2AF2; TCERG1; UTP14A; SRSF10; SAP1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PHGDH is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 92%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Tsang, H.T., (2006) Genomics 88 (3), 333-346

Shipping Conditions

Wet Ice

Protein Length

533

NCBI Gene Symbol

PHGDH

NCBI GB Accession Number

PHGDH

Host or Source

Rabbit

Protein Name

D-3-phosphoglycerate dehydrogenase

Nucleotide Accession Number

NM_006623

Peptide Sequence

CAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQF

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