SFN Antibody - middle region : Biotin (ARP54792_P050-Biotin)

Product Specifications

Gene Name

Stratifin

Gene Aliases

YWHAS

Gene ID

2810

Swiss Prot

P31947

Accession Number

NP_006133

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SFN

Target

SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

Partner Proteins

FAM9B; RAB3IP; LONRF1; CCDC102B; ZC2HC1C; DTL; FAM53C; MKRN3; FOXO4; MAGEA1; CCNH; SIK3; ZFYVE19; YWHAZ; VCL; UBE2V1; SNRPF; UBE2R2; PAK2; G6PD; TARDBP; EGFR; BAD; MARK3; HDAC7; HDAC5; HDAC4; RAF1; CDC25C; MST1R; ABL1; HNRNPD; ATF2; TRIM32; COPS6; UBC; TP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.