SFN Antibody - middle region : Biotin (ARP54792_P050-Biotin)
Product Specifications
Gene Name
Stratifin
Gene Aliases
YWHAS
Gene ID
2810
Swiss Prot
P31947
Accession Number
NP_006133
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SFN
Target
SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Partner Proteins
FAM9B; RAB3IP; LONRF1; CCDC102B; ZC2HC1C; DTL; FAM53C; MKRN3; FOXO4; MAGEA1; CCNH; SIK3; ZFYVE19; YWHAZ; VCL; UBE2V1; SNRPF; UBE2R2; PAK2; G6PD; TARDBP; EGFR; BAD; MARK3; HDAC7; HDAC5; HDAC4; RAF1; CDC25C; MST1R; ABL1; HNRNPD; ATF2; TRIM32; COPS6; UBC; TP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 93%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
References & Citations
Yang, W., (2008) Cell Cycle 7 (5), 670-682
Shipping Conditions
Wet Ice
Protein Length
248
NCBI Gene Symbol
SFN
NCBI GB Accession Number
SFN
Host or Source
Rabbit
Protein Name
14-3-3 protein sigma
Nucleotide Accession Number
NM_006142
Peptide Sequence
FHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLT
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