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LGALS3BP Antibody - middle region : FITC (ARP54779_P050-FITC)

Product Specifications

Gene Name

Galectin 3 binding protein

Gene Aliases

90K, M2BP, gp90, CyCAP, BTBD17B, MAC-2-BP, TANGO10B

Gene ID

3959

Swiss Prot

Q08380

Accession Number

NP_005558

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LGALS3BP

Target

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) . It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

Partner Proteins

GIGYF2; PRRC2C; CCT5; TUBB; CRTC2; RAVER1; TUBA1C; ENAH; CEP55; XRN2; CEP250; MAGED2; CCT8; CCT2; CCT4; CCT7; TUBGCP3; TUBB4B; TRAP1; BAG2; RPL23; IRS4; TUBA1A; MOGS; CCT3; TCP1; RPS4X; RPL38; HSPD1; HSP90AB1; HSP90AA1; HSPA8; HSPA5; HSPA1A; HNRNPU; CCT6A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 83%; Human: 100%; Mouse: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

63kDa

References & Citations

Lee, Y.J., Clin. Exp. Rheumatol. 25 (4 SUPPL 45), S41-S45 (2007)

Shipping Conditions

Wet Ice

Protein Length

585

NCBI Gene Symbol

LGALS3BP

NCBI GB Accession Number

LGALS3BP

Host or Source

Rabbit

Protein Name

Galectin-3-binding protein

Nucleotide Accession Number

NM_005567

Peptide Sequence

NLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTS

Frequently Asked Questions

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