LGALS3BP Antibody - middle region : FITC (ARP54779_P050-FITC)
Product Specifications
Gene Name
Galectin 3 binding protein
Gene Aliases
90K, M2BP, gp90, CyCAP, BTBD17B, MAC-2-BP, TANGO10B
Gene ID
3959
Swiss Prot
Q08380
Accession Number
NP_005558
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human LGALS3BP
Target
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV) . It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
Partner Proteins
GIGYF2; PRRC2C; CCT5; TUBB; CRTC2; RAVER1; TUBA1C; ENAH; CEP55; XRN2; CEP250; MAGED2; CCT8; CCT2; CCT4; CCT7; TUBGCP3; TUBB4B; TRAP1; BAG2; RPL23; IRS4; TUBA1A; MOGS; CCT3; TCP1; RPS4X; RPL38; HSPD1; HSP90AB1; HSP90AA1; HSPA8; HSPA5; HSPA1A; HNRNPU; CCT6A
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 83%; Dog: 83%; Human: 100%; Mouse: 100%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
References & Citations
Lee, Y.J., Clin. Exp. Rheumatol. 25 (4 SUPPL 45), S41-S45 (2007)
Shipping Conditions
Wet Ice
Protein Length
585
NCBI Gene Symbol
LGALS3BP
NCBI GB Accession Number
LGALS3BP
Host or Source
Rabbit
Protein Name
Galectin-3-binding protein
Nucleotide Accession Number
NM_005567
Peptide Sequence
NLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTS
Frequently Asked Questions
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