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H1F0 Antibody - N-terminal region : Biotin (ARP54754_P050-Biotin)

Product Specifications

Gene Name

H1 histone family, member 0

Gene Aliases

H10, H1.0, H1F0, H1FV

Gene ID

3005

Swiss Prot

P07305

Accession Number

NP_005309

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human H1F0

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H1F0 gene is intronless and encodes a member of the histone H1 family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; LIN28A; POP1; PRKRA; SUZ12; EED; RNF2; PARK2; ERCC8; PRKCB; CDK1; APP; CDK2; CDK4; CAND1; PfPK6; YWHAZ; CDK5; CCNE1; HDGF; Nedd4; NEDD4L; GRB2; YWHAQ; XBP1; IKBKG; NOA1; IPO7; RAD51B; KPNB1; IPO5; KPNA2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

194

NCBI Gene Symbol

H1F0

NCBI GB Accession Number

H1F0

Host or Source

Rabbit

Protein Name

Histone H1.0

Nucleotide Accession Number

NM_005318

Peptide Sequence

IQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTK

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