GBP2 Antibody - N-terminal region : Biotin (ARP54714_P050-Biotin)
Selected Variant
ARP54714_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Guanylate binding protein 2, interferon-inducible
Gene ID
2634
Swiss Prot
P32456
Accession Number
NP_004111
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GBP2
Target
GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) . GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs) . GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) . The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
Partner Proteins
CNDP2; NANS; RPS6KA1; PEPD; MVD; GSR; GNS; GLA; G6PD; CASP7; CAPN1; ASS1; GSK3B; GADD45A; CSNK2B; BNIP3L; BID; ANXA7; MAPK8IP2; STK3; KLHL20; BTBD2; LSM2; PAFAH1B3; PPP1R8; MAGI1; TFG; SERPINB9; SEPHS1; FXR1; HSPE1; SAT1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 79%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
67kDa
References & Citations
Lukasiewicz, R., (2007) J. Biol. Chem. 282 (32), 23036-23043
Shipping Conditions
Wet Ice
Protein Length
591
NCBI Gene Symbol
GBP2
NCBI GB Accession Number
GBP2
Host or Source
Rabbit
Protein Name
Interferon-induced guanylate-binding protein 2
Nucleotide Accession Number
NM_004120
Peptide Sequence
HTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLS
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