FKBP5 Antibody - middle region : Biotin (ARP54712_P050-Biotin)
Selected Variant
ARP54712_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
FK506 binding protein 5
Gene Aliases
P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10
Gene ID
2289
Swiss Prot
Q13451
Accession Number
NP_004108
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human FKBP5
Target
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites.
Partner Proteins
LRRC40; CXorf57; EGLN1; AGO2; CACYBP; CHORDC1; AGO1; KIAA1279; NUDCD3; GLMN; CDC37; SUGT1; PTGES3; NUDC; AHSA1; DNAJB6; AURKB; IKBKG; IRS4; TUBA1A; TTC4; PYGL; PDCD2; CDK11A; HGH1; C14orf80; MCMBP; PNPLA2; ANKMY2; CDC37L1; MCM4; ILK; HSP90AB1; HSP90AA1; H
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
Shipping Conditions
Wet Ice
Protein Length
457
NCBI Gene Symbol
FKBP5
NCBI GB Accession Number
FKBP5
Host or Source
Rabbit
Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP5
Nucleotide Accession Number
NM_004117
Peptide Sequence
KMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW
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