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LGALS3 Antibody - N-terminal region : Biotin (ARP54688_P050-Biotin)

Selected Variant

ARP54688_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Galectin 3

Gene Aliases

L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2

Gene ID

3958

Swiss Prot

P17931

Accession Number

NP_002297

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3

Target

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Partner Proteins

PRR13; SS18L1; PPIG; LGALS3; GOLGA2; MAP1LC3A; SQSTM1; RAB7A; LAMP1; EGFR; CFTR; PAXIP1; BARD1; AGPS; IGBP1; GTF2I; CLNS1A; APP; SLC25A5; ACTA1; MYOC; LGALS3BP; CYHR1; GEMIN4; SUFU; CUBN; CSNK1A1; LIM2; FCGR2A; ELN; MMP2; CSNK2A2; CSNK2A1; C1GALT1C1; LGAL

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

LGALS3 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

References & Citations

Bartolazzi, A., (2008) Lancet Oncol. 9 (6), 543-549

Shipping Conditions

Wet Ice

Protein Length

250

NCBI Gene Symbol

LGALS3

NCBI GB Accession Number

LGALS3

Host or Source

Rabbit

Protein Name

Galectin-3

Nucleotide Accession Number

NM_002306

Peptide Sequence

GASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPG

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