HSPA6 Antibody - middle region : HRP (ARP54649_P050-HRP)
Product Specifications
Gene Name
Heat shock 70kDa protein 6 (HSP70B')
Gene Aliases
HSP70B'
Gene ID
3310
Swiss Prot
P17066
Accession Number
NP_002146
Host
Rabbit
Reactivity
Human, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HSPA6
Target
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Partner Proteins
TP53; MLF2; UBC; HSPA1A; HSPA8; HDAC6; ADCK5; CYP4F12; env; DNAJB4; IQCB1; UBL4A; NOS2; CISH; CFTR; TRAF3IP1; HSP90AA1; SCFD1; HSPA5; HSPA1L; SHC1; PIK3R2; INPPL1; CRK; AP2M1; CBL; COPS5; CUL1; NEDD8; TERF1; PARD3; ARRB2; INSIG2; DYRK2; RFWD2; RPAP3; MEPC
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%; Pig: 79%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
71kDa
References & Citations
Noonan, E.J., (2007) Cell Stress Chaperones 12 (4), 393-402
Shipping Conditions
Wet Ice
Protein Length
643
NCBI Gene Symbol
HSPA6
NCBI GB Accession Number
HSPA6
Host or Source
Rabbit
Protein Name
Heat shock 70 kDa protein 6
Nucleotide Accession Number
NM_002155
Peptide Sequence
EYEHQKRELEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEV
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