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HSPA6 Antibody - middle region : Biotin (ARP54649_P050-Biotin)

Product Specifications

Gene Name

Heat shock 70kDa protein 6 (HSP70B')

Gene Aliases

HSP70B'

Gene ID

3310

Swiss Prot

P17066

Accession Number

NP_002146

Host

Rabbit

Reactivity

Human, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HSPA6

Target

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.

Partner Proteins

TP53; MLF2; UBC; HSPA1A; HSPA8; HDAC6; ADCK5; CYP4F12; env; DNAJB4; IQCB1; UBL4A; NOS2; CISH; CFTR; TRAF3IP1; HSP90AA1; SCFD1; HSPA5; HSPA1L; SHC1; PIK3R2; INPPL1; CRK; AP2M1; CBL; COPS5; CUL1; NEDD8; TERF1; PARD3; ARRB2; INSIG2; DYRK2; RFWD2; RPAP3; MEPC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Pig: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

71kDa

References & Citations

Noonan, E.J., (2007) Cell Stress Chaperones 12 (4), 393-402

Shipping Conditions

Wet Ice

Protein Length

643

NCBI Gene Symbol

HSPA6

NCBI GB Accession Number

HSPA6

Host or Source

Rabbit

Protein Name

Heat shock 70 kDa protein 6

Nucleotide Accession Number

NM_002155

Peptide Sequence

EYEHQKRELEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEV

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