EPS15 Antibody - C-terminal region : Biotin (ARP54601_P050-Biotin)

Product Specifications

Gene Name

Epidermal growth factor receptor pathway substrate 15

Gene Aliases

AF1P, AF-1P, MLLT5

Gene ID

2060

Swiss Prot

P42566

Accession Number

NP_001972

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human EPS15

Target

EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

TRIM63; UBC; GJA1; EPHA2; CORO7; RNF11; RABL6; OPTN; LAPTM5; VCAM1; ITGA4; FN1; Fcho2; Dab2; STON2; EPN1; AGFG1; EPS15; CRKL; CRK; AP2S1; AP2M1; AP2B1; AP1B1; AP2A2; AP2A1; ACTB; ABL1; NECAP1; SPG20; VPRBP; KRT75; IQGAP1; KRT36; KRT37; KRT38; CCT3; TRAF2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

EPS15 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.