MRPL58 Antibody - middle region : HRP (ARP54583_P050-HRP)
Product Specifications
Gene Name
Mitochondrial ribosomal protein L58
Gene Aliases
DS1, DS-1, ICT1, MRP-L58
Gene ID
3396
Swiss Prot
Q14197
Accession Number
NP_001536
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ICT1
Target
The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; LIN28A; MRPS6; MRPS27; DAP3; MRPS18B; MRPL3; MRPL12; NPM1; MTHFD1; SYNCRIP; FLOT1; PPT2; RPL14; EIF4H; UQCRFS1; SRSF3; RPS18; RPS15; MRPL23; RPL4; RPL3; NDUFB7; NDUFB5; NDUFA2; ILF2; HNRNPU; CYC1; CLPTM1; CDH2; CALU; APP; ERGIC1; DDX28; SYNJ2BP; MRPL
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
23kDa
References & Citations
Van (1995) Eur. J. Biochem. 234 (3), 843-848
Shipping Conditions
Wet Ice
Protein Length
206
NCBI Gene Symbol
MRPL58
NCBI GB Accession Number
MRPL58
Host or Source
Rabbit
Protein Name
Peptidyl-tRNA hydrolase ICT1, mitochondrial
Nucleotide Accession Number
NM_001545
Peptide Sequence
AEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDM
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