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MRPL58 Antibody - middle region : FITC (ARP54583_P050-FITC)

Product Specifications

Gene Name

Mitochondrial ribosomal protein L58

Gene Aliases

DS1, DS-1, ICT1, MRP-L58

Gene ID

3396

Swiss Prot

Q14197

Accession Number

NP_001536

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ICT1

Target

The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; LIN28A; MRPS6; MRPS27; DAP3; MRPS18B; MRPL3; MRPL12; NPM1; MTHFD1; SYNCRIP; FLOT1; PPT2; RPL14; EIF4H; UQCRFS1; SRSF3; RPS18; RPS15; MRPL23; RPL4; RPL3; NDUFB7; NDUFB5; NDUFA2; ILF2; HNRNPU; CYC1; CLPTM1; CDH2; CALU; APP; ERGIC1; DDX28; SYNJ2BP; MRPL

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

References & Citations

Van (1995) Eur. J. Biochem. 234 (3), 843-848

Shipping Conditions

Wet Ice

Protein Length

206

NCBI Gene Symbol

MRPL58

NCBI GB Accession Number

MRPL58

Host or Source

Rabbit

Protein Name

Peptidyl-tRNA hydrolase ICT1, mitochondrial

Nucleotide Accession Number

NM_001545

Peptide Sequence

AEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDM

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