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PELI3 Antibody - N-terminal region : Biotin (ARP54532_P050-Biotin)

Product Specifications

Gene Name

Pellino E3 ubiquitin protein ligase family member 3

Gene Aliases

MGC35521

Gene ID

246330

Swiss Prot

Q8N2H9-2

Accession Number

NP_001091980

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PELI3

Target

Toll-like receptors (TLRs) and IL1R (IL1R1) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R.Toll-like receptors (TLRs; see MIM 603030) and IL1R (IL1R1; MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]) .[supplied by OMIM].

Partner Proteins

RIPK2; UBE2V1; UBE2N; IRAK1; APP; TRAF6; MAP3K14; MAP3K7; IRAK4; UBC; IRAK2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Guinea Pig: 93%; Horse: 85%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Butler, M.P., (2005) J. Biol. Chem. 280 (30), 27759-27768

Shipping Conditions

Wet Ice

Protein Length

445

NCBI Gene Symbol

PELI3

NCBI GB Accession Number

PELI3

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase pellino homolog 3

Nucleotide Accession Number

NM_001098510

Peptide Sequence

VLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLG

Frequently Asked Questions

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