ARSA Antibody - middle region : FITC (ARP54529_P050-FITC)
Selected Variant
ARP54529_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Arylsulfatase A
Gene Aliases
ASA, MLD
Gene ID
410
Swiss Prot
P15289
Accession Number
NP_001078896
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ARSA
Target
ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD) .The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.
Partner Proteins
TRIP13; PPIC; CETN2; CLEC4G; ARSA; GAL3ST1; BMPR2; CTSL
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 92%; Rabbit: 79%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
52kDa
References & Citations
Saito, S., (2008) Mol. Genet. Metab. 93 (4), 419-425
Shipping Conditions
Wet Ice
Protein Length
507
NCBI Gene Symbol
ARSA
NCBI GB Accession Number
ARSA
Host or Source
Rabbit
Protein Name
Arylsulfatase A
Nucleotide Accession Number
NM_001085427
Peptide Sequence
KQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPH
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