NLRP1 Antibody: FITC (ARP54479_P050-FITC)
Product Specifications
Gene Name
NLR family, pyrin domain containing 1
Gene Aliases
NAC, JRRP, MSPC, AIADK, CARD7, CIDED, NALP1, SLEV1, DEFCAP, PP1044, VAMAS1, CLR17.1, DEFCAP-L/S
Gene ID
22861
Swiss Prot
Q9C000
Accession Number
NP_001028225
Host
Rabbit
Reactivity
Human, Cow, Dog, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence AAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHL
Target
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Partner Proteins
TRIM68; CUL3; APOA1; NLRP1; PYCARD; NOD1; CASP5; CASP9; APAF1; CASP2; BCL2L1; BCL2; CASP1; NLRC4
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 85%; Dog: 100%; Horse: 79%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
166 kDa
Shipping Conditions
Wet Ice
Protein Length
1473
NCBI Gene Symbol
NLRP1
Protein Name
NACHT, LRR and PYD domains-containing protein 1
Nucleotide Accession Number
NM_001033053
Curated Selection
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