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NLRP1 Antibody : FITC (ARP54479_P050-FITC)

Selected Variant

ARP54479_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

NLR family, pyrin domain containing 1

Gene Aliases

NAC, JRRP, MSPC, AIADK, CARD7, CIDED, NALP1, SLEV1, DEFCAP, PP1044, VAMAS1, CLR17.1, DEFCAP-L/S

Gene ID

22861

Swiss Prot

Q9C000

Accession Number

NP_001028225

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence AAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHL

Target

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Partner Proteins

TRIM68; CUL3; APOA1; NLRP1; PYCARD; NOD1; CASP5; CASP9; APAF1; CASP2; BCL2L1; BCL2; CASP1; NLRC4

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 100%; Horse: 79%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

166 kDa

Shipping Conditions

Wet Ice

Protein Length

1473

NCBI Gene Symbol

NLRP1

NCBI GB Accession Number

NLRP1

Host or Source

Rabbit

Protein Name

NACHT, LRR and PYD domains-containing protein 1

Nucleotide Accession Number

NM_001033053

Peptide Sequence

AAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHL

Price

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