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CENPP Antibody - N-terminal region : HRP (ARP54412_P050-HRP)

Product Specifications

Gene Name

Centromere protein P

Gene Aliases

CENP-P

Gene ID

401541

Swiss Prot

Q6IPU0

Accession Number

NP_001012267

Host

Rabbit

Reactivity

Human, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CENPP

Target

CENPP is the component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENPP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.CENPP is a subunit of a CENPH (MIM 605607) -CENPI (MIM 300065) -associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]) .[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1104 CR592049.1 1-1104 1105-1633 BC071726.1 622-1150 1634-1689 BX537851.1 972-1027 1690-3411 AK091247.1 839-2560 3412-3428 AL833701.1 3078-3094

Partner Proteins

KLC3; ZNF341; USHBP1; CCDC33; CENPO; TEX11; RPIA; NHLH1; GOLGA2; CENPU; CENPM; CENPN; CENPH; CENPQ; ITGB3BP; CENPI; UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 77%; Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

Okada, M., (2006) Nat. Cell Biol. 8 (5), 446-457

Shipping Conditions

Wet Ice

Product Datasheet

Anti-CENPP (ARP54412_P050-HRP) antibody

Protein Length

288

NCBI Gene Symbol

CENPP

NCBI GB Accession Number

CENPP

Host or Source

Rabbit

Protein Name

Centromere protein P

Nucleotide Accession Number

NM_001012267

Peptide Sequence

VQKSFQAIHQFNLEGWKSSKDLKNQLGHLESELSFLSTLTGINIRNHSKQ

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