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IMPDH1 Antibody - middle region : HRP (ARP54363_P050-HRP)

Product Specifications

Gene Name

IMP (inosine 5'-monophosphate) dehydrogenase 1

Gene Aliases

IMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608

Gene ID

3614

Swiss Prot

P20839

Accession Number

NP_899066

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IMPDH1

Target

IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP) . This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10) .

Partner Proteins

UBC; LAMP2; IMPDH2; XRCC6; GMNN; HTRA1; DDX3X; SUMO4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

IMPDH1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62kDa

References & Citations

Wang, J., (2008) Clin. Pharmacol. Ther. 83 (5), 711-717

Shipping Conditions

Wet Ice

Protein Length

563

NCBI Gene Symbol

IMPDH1

NCBI GB Accession Number

IMPDH1

Host or Source

Rabbit

Protein Name

Inosine-5'-monophosphate dehydrogenase 1

Nucleotide Accession Number

NM_183243

Peptide Sequence

KKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE

Frequently Asked Questions

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