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ALAS1 Antibody - N-terminal region : FITC (ARP54346_P050-FITC)

Selected Variant

ARP54346_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Aminolevulinate, delta-, synthase 1

Gene Aliases

ALAS, MIG4, ALAS3, ALASH, ALAS-H

Gene ID

211

Swiss Prot

P13196

Accession Number

NP_000679

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1

Target

Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

Partner Proteins

FAM127C; KLHL35; ZNF564; TEKT4; DUSP19; SNX20; MTFR2; LONRF1; ZMAT1; CDC73; TTC23; CERK; SH2D4A; EP400; C2orf42; GNL3L; CCHCR1; POLDIP2; ZFYVE26; USP20; TMSB10; ZNF175; WIPF1; UBC; TMSB4XP6; TMSB4XP2; TMSB4XP1; TMSB4X; TCEA2; PPL; BCL7A; ALAS1; PLAU; VHL

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

References & Citations

Jung, M., (2007) Urologe A 46 (9), 1083-1084

Shipping Conditions

Wet Ice

Protein Length

640

NCBI Gene Symbol

ALAS1

NCBI GB Accession Number

ALAS1

Host or Source

Rabbit

Protein Name

5-aminolevulinate synthase, nonspecific, mitochondrial

Nucleotide Accession Number

NM_000688

Peptide Sequence

ETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVS

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