ALAS1 Antibody - N-terminal region : Biotin (ARP54346_P050-Biotin)
Product Specifications
Gene Name
Aminolevulinate, delta-, synthase 1
Gene Aliases
ALAS, MIG4, ALAS3, ALASH, ALAS-H
Gene ID
211
Swiss Prot
P13196
Accession Number
NP_000679
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ALAS1
Target
Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Partner Proteins
FAM127C; KLHL35; ZNF564; TEKT4; DUSP19; SNX20; MTFR2; LONRF1; ZMAT1; CDC73; TTC23; CERK; SH2D4A; EP400; C2orf42; GNL3L; CCHCR1; POLDIP2; ZFYVE26; USP20; TMSB10; ZNF175; WIPF1; UBC; TMSB4XP6; TMSB4XP2; TMSB4XP1; TMSB4X; TCEA2; PPL; BCL7A; ALAS1; PLAU; VHL
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
70kDa
References & Citations
Jung, M., (2007) Urologe A 46 (9), 1083-1084
Shipping Conditions
Wet Ice
Protein Length
640
NCBI Gene Symbol
ALAS1
NCBI GB Accession Number
ALAS1
Host or Source
Rabbit
Protein Name
5-aminolevulinate synthase, nonspecific, mitochondrial
Nucleotide Accession Number
NM_000688
Peptide Sequence
ETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVS
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