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IL6 Antibody - middle region : FITC (ARP54339_P050-FITC)

Selected Variant

ARP54339_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Interleukin 6

Gene Aliases

CDF, HGF, HSF, BSF2, IL-6, BSF-2, IFNB2, IFN-beta-2

Gene ID

3569

Swiss Prot

P05231

Accession Number

NP_000591

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IL6

Target

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.

Partner Proteins

ZBTB16; SH3GL2; IL6ST; PTHLH; IL6R

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23 kDa

Shipping Conditions

Wet Ice

Protein Length

212

NCBI Gene Symbol

IL6

NCBI GB Accession Number

IL6

Host or Source

Rabbit

Protein Name

Interleukin-6

Nucleotide Accession Number

NM_000600.3

Peptide Sequence

CFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVL

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