LIG1 Antibody - middle region : FITC (ARP54308_P050-FITC)
Selected Variant
ARP54308_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
DNA ligase 1
Gene ID
3978
Swiss Prot
P18858
Accession Number
NP_000225
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human LIG1
Target
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Partner Proteins
PCNA; UBC; PRMT3; SUMO2; RGS2; TUBB3; MRE11A; INPP1; CSNK2A1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
LIG1 is supported by BioGPS gene expression data to be expressed in A549
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 92%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 85%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
102kDa
Shipping Conditions
Wet Ice
Protein Length
919
NCBI Gene Symbol
LIG1
NCBI GB Accession Number
LIG1
Host or Source
Rabbit
Protein Name
DNA ligase 1
Nucleotide Accession Number
NM_000234
Peptide Sequence
PSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAF
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