JAK3 Antibody - N-terminal region : Biotin (ARP54305_P050-Biotin)
Selected Variant
ARP54305_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Janus kinase 3
Gene Aliases
JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Gene ID
3718
Swiss Prot
Q8N1E8
Accession Number
NP_000206.2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human JAK3
Target
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
Shipping Conditions
Wet Ice
Protein Length
619
NCBI Gene Symbol
JAK3
NCBI GB Accession Number
JAK3
Host or Source
Rabbit
Protein Name
Tyrosine-protein kinase JAK3
Nucleotide Accession Number
NM_000215.3
Peptide Sequence
APPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAE
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