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ERCC5 Antibody - N-terminal region : Biotin (ARP54287_P050-Biotin)

Product Specifications

Gene Name

Excision repair cross-complementing rodent repair deficiency, complementation group 5

Gene Aliases

XPG, UVDR, XPGC, COFS3, ERCM2, ERCC5-201

Gene ID

2073

Swiss Prot

P28715

Accession Number

NP_000114

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC5

Target

Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; CDK7; GTF2H1; POLR2A; EWSR1; ERCC6; SUMO2; PIDD1; BCL6; TAF10; ERCC3; NTHL1; GTF2H4; PCNA; ERCC2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

133kDa

References & Citations

Sasaki, M., (2008) Neoplasia 10 (3), 255-265

Shipping Conditions

Wet Ice

Protein Length

1186

NCBI Gene Symbol

ERCC5

NCBI GB Accession Number

ERCC5

Host or Source

Rabbit

Protein Name

DNA repair protein complementing XP-G cells

Nucleotide Accession Number

NM_000123

Peptide Sequence

NPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQ

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