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EPHX1 Antibody - middle region : Biotin (ARP54286_P050-Biotin)

Product Specifications

Gene Name

Epoxide hydrolase 1, microsomal (xenobiotic)

Gene Aliases

MEH, EPHX, EPOX, HYL1

Gene ID

2052

Swiss Prot

P07099

Accession Number

NP_000111

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human EPHX1

Target

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Epoxide hydrolase plays an important role in both the activation and detoxification of exogenous chemicals such as polycyclic aromatic hydrocarbons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

RNF2; ATP4A; UBC; HPDL; CDKN2AIP; DNAJB11; SUMO1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Luo, B., (2008) J. Mol. Biol. 380 (1), 31-41

Shipping Conditions

Wet Ice

Protein Length

455

NCBI Gene Symbol

EPHX1

NCBI GB Accession Number

EPHX1

Host or Source

Rabbit

Protein Name

Epoxide hydrolase 1

Nucleotide Accession Number

NM_000120

Peptide Sequence

CPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLI

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