ATG16L1 Antibody - N-terminal region : Biotin (ARP54268_P050-Biotin)

Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]) .[supplied by OMIM].

WIPI2; RB1CC1; DEDD2; TRAF3IP3; NOD2; TMEM59; TLR2; SUMO2; ATG13; ATG5; ULK1; UBC; TNK2; SYNPO2; ATG12; NOD1; WDFY3; APP; RAB33B; RAB35; RAB3D; RAB33A; HSPA4; FCGRT; CLTC; AP2M1; ELAVL1; MAP1LC3C; MAP1LC3B; ATG3; CCT2; CCT7; AGPS; GAN; CCT3; SNAPC4; ATG16

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.