ATG5 Antibody - C-terminal region : Biotin (ARP54267_P050-Biotin)
Product Specifications
Gene Name
ATG5 autophagy related 5 homolog (S. cerevisiae)
Gene Aliases
ASP, APG5, APG5L, hAPG5, SCAR25, APG5-LIKE
Gene ID
9474
Swiss Prot
Q9H1Y0
Accession Number
NP_004840
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ATG5
Target
ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Partner Proteins
TEKT4; CCHCR1; WIPI2; KEAP1; VCP; MEOX2; FADD; ATG16L1; RB1CC1; EXOC4; ATG3; ATG12; CAV1; HTT; WDFY3; TAB3; TAB2; TECPR1; ELAVL1; UBC; SIRT1; TKT; MAP1LC3C; MAP1LC3B; ATG10; ATG5; IMPDH2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
References & Citations
Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)
Shipping Conditions
Wet Ice
Protein Length
275
NCBI Gene Symbol
ATG5
NCBI GB Accession Number
ATG5
Host or Source
Rabbit
Protein Name
Autophagy protein 5
Nucleotide Accession Number
NM_004849
Peptide Sequence
DPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD
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