PAOX Antibody - middle region : HRP (ARP53848_P050-HRP)
Selected Variant
ARP53848_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Polyamine oxidase (exo-N4-amino)
Gene Aliases
PAO
Gene ID
196743
Swiss Prot
Q6QHF9-4
Accession Number
NP_997011
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PAOX
Target
PAOX belongs to the flavin monoamine oxidase family. PAOX is a flavoenzyme which catalyzes the oxidation of N (1) -acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N (1) -acetylspermidine to putrescine. PAOX does not oxidize spermidine. It plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Partner Proteins
PEX5
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53kDa
References & Citations
Jarvinen, A., (2006) J. Biol. Chem. 281 (8), 4589-4595
Shipping Conditions
Wet Ice
Protein Length
486
NCBI Gene Symbol
PAOX
NCBI GB Accession Number
PAOX
Host or Source
Rabbit
Protein Name
Peroxisomal N (1) -acetyl-spermine/spermidine oxidase
Nucleotide Accession Number
NM_207128
Peptide Sequence
RGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLL
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