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PAOX Antibody - middle region : Biotin (ARP53848_P050-Biotin)

Product Specifications

Gene Name

Polyamine oxidase (exo-N4-amino)

Gene Aliases

PAO

Gene ID

196743

Swiss Prot

Q6QHF9-4

Accession Number

NP_997011

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PAOX

Target

PAOX belongs to the flavin monoamine oxidase family. PAOX is a flavoenzyme which catalyzes the oxidation of N (1) -acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N (1) -acetylspermidine to putrescine. PAOX does not oxidize spermidine. It plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

Partner Proteins

PEX5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Jarvinen, A., (2006) J. Biol. Chem. 281 (8), 4589-4595

Shipping Conditions

Wet Ice

Protein Length

486

NCBI Gene Symbol

PAOX

NCBI GB Accession Number

PAOX

Host or Source

Rabbit

Protein Name

Peroxisomal N (1) -acetyl-spermine/spermidine oxidase

Nucleotide Accession Number

NM_207128

Peptide Sequence

RGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLL

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