PAOX Antibody - C-terminal region : Biotin (ARP53830_P050-Biotin)
Product Specifications
Gene Name
Polyamine oxidase (exo-N4-amino)
Gene Aliases
PAO
Gene ID
196743
Swiss Prot
Q5VWY0
Accession Number
NP_690875
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PAOX
Target
PAOX belongs to the flavin monoamine oxidase family. PAOX is a flavoenzyme which catalyzes the oxidation of N (1) -acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N (1) -acetylspermidine to putrescine. PAOX does not oxidize spermidine. It plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Partner Proteins
PEX5
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
References & Citations
Jarvinen, A., (2006) J. Biol. Chem. 281 (8), 4589-4595
Shipping Conditions
Wet Ice
Protein Length
511
NCBI Gene Symbol
PAOX
NCBI GB Accession Number
PAOX
Host or Source
Rabbit
Protein Name
Peroxisomal N (1) -acetyl-spermine/spermidine oxidase
Nucleotide Accession Number
NM_152911
Peptide Sequence
VGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWRE
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