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IFT122 Antibody - C-terminal region : Biotin (ARP53817_P050-Biotin)

Product Specifications

Gene Name

Intraflagellar transport 122 homolog (Chlamydomonas)

Gene Aliases

CED, SPG, CED1, FAP80, WDR10, WDR10p, WDR140

Gene ID

55764

Swiss Prot

Q9HBG6

Accession Number

NP_443716

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human IFT122

Target

IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. IFT122 contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

UBC; gag-pol

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

129kDa

References & Citations

Gross, C., (2001) DNA Cell Biol. 20 (1), 41-52

Shipping Conditions

Wet Ice

Protein Length

1131

NCBI Gene Symbol

IFT122

NCBI GB Accession Number

IFT122

Host or Source

Rabbit

Protein Name

Intraflagellar transport protein 122 homolog

Nucleotide Accession Number

NM_052990

Peptide Sequence

QADPAQKDTMLGKFYHFQRLAELYHGYHAIHRHTEDPFSVHRPETLFNIS

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