APH1B Antibody - N-terminal region : FITC (ARP53807_P050-FITC)
Selected Variant
ARP53807_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Anterior pharynx defective 1 homolog B (C. elegans)
Gene Aliases
PSFL, APH-1B, PRO1328, TAAV688
Gene ID
83464
Swiss Prot
Q8WW43
Accession Number
NP_112591
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human APH1B
Target
This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Partner Proteins
UBC; PSENEN; NCSTN; PSEN2; PSEN1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
Shipping Conditions
Wet Ice
Protein Length
257
NCBI Gene Symbol
APH1B
NCBI GB Accession Number
APH1B
Host or Source
Rabbit
Protein Name
Gamma-secretase subunit APH-1B
Nucleotide Accession Number
NM_031301
Peptide Sequence
IIDNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGE
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