FBXO31 Antibody - middle region: FITC (ARP53775_P050-FITC)
Product Specifications
Gene Name
F-box protein 31
Gene Aliases
FBX14, Fbx31, MRT45, FBXO14, pp2386
Gene ID
79791
Swiss Prot
Q5XUX0
Accession Number
NP_079011
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
Target
FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Partner Proteins
CDT1; UBE2L6; UBE2D1; CCND1; CUL1; MAP2K6; PARD6A; SKP1; COPS5; RBX1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
Shipping Conditions
Wet Ice
Protein Length
367
NCBI Gene Symbol
FBXO31
Protein Name
F-box only protein 31
Nucleotide Accession Number
NM_024735
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