FBXO31 Antibody - middle region : FITC (ARP53775_P050-FITC)
Selected Variant
ARP53775_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
F-box protein 31
Gene Aliases
FBX14, Fbx31, MRT45, FBXO14, pp2386
Gene ID
79791
Swiss Prot
Q5XUX0
Accession Number
NP_079011
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
Target
FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Partner Proteins
CDT1; UBE2L6; UBE2D1; CCND1; CUL1; MAP2K6; PARD6A; SKP1; COPS5; RBX1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
Shipping Conditions
Wet Ice
Protein Length
367
NCBI Gene Symbol
FBXO31
NCBI GB Accession Number
FBXO31
Host or Source
Rabbit
Protein Name
F-box only protein 31
Nucleotide Accession Number
NM_024735
Peptide Sequence
QGPRESQPSPAQPRAEAPSKGPDGTPGEDGGEPGDAVAAAEQPAQCGQGQ
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