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ISYNA1 Antibody - N-terminal region : HRP (ARP53716_P050-HRP)

Selected Variant

ARP53716_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Inositol-3-phosphate synthase 1

Gene Aliases

IPS, INO1, INOS, IPS 1, IPS-1

Gene ID

51477

Swiss Prot

Q9NPH2

Accession Number

NP_057452

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ISYNA1

Target

Myoinositol, the most common naturally occurring form of inositol, is a component of plasma membrane phospholipids and functions as a cell signaling molecule. ISYNA1 (EC 5.5.1.4), or IPS, is a rate-limiting enzyme that catalyzes the de novo synthesis of myoinositol 1-phosphate from glucose 6-phosphate.Myoinositol, the most common naturally occurring form of inositol, is a component of plasma membrane phospholipids and functions as a cell signaling molecule. ISYNA1 (EC 5.5.1.4), or IPS, is a rate-limiting enzyme that catalyzes the de novo synthesis of myoinositol 1-phosphate from glucose 6-phosphate (Seelan et al., 2004 [PubMed 15464731]) .[supplied by OMIM].

Partner Proteins

TRAF4; UBC; DUSP14; POT1; PPP2CA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ISYNA1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rat: 86%; Yeast: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Seelan, R.S., (2004) Arch. Biochem. Biophys. 431 (1), 95-106

Shipping Conditions

Wet Ice

Protein Length

558

NCBI Gene Symbol

ISYNA1

NCBI GB Accession Number

ISYNA1

Host or Source

Rabbit

Protein Name

Inositol-3-phosphate synthase 1

Nucleotide Accession Number

NM_016368

Peptide Sequence

LQEQLWPHMEALRPRPSVYIPEFIAANQSARADNLIPGSRAQQLEQIRRD

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