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FEM1B Antibody - C-terminal region : FITC (ARP53703_P050-FITC)

Product Specifications

Gene Name

Fem-1 homolog b (C. elegans)

Gene Aliases

F1AA, F1A-ALPHA, FEM1-beta

Gene ID

10116

Swiss Prot

Q9UK73

Accession Number

NP_056137

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FEM1B

Target

FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. FEM1B also involved in glucose homeostasis in pancreatic islet.

Partner Proteins

GLI1; HIF1AN; NKX3-1; fem-2; Ppm1f; UBC; RBX1; CUL2; TCEB2; TCEB1; Tnfrsf1a; Fem1b; Fas; Casp3; COPS4; RAD9A; CHEK1; DCUN1D1; COPS5; COPS6; CUL5; NEDD8; KIAA0319; GNB2L1; APAF1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

FEM1B is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Kamura, T., (2004) Genes Dev. 18 (24), 3055-3065

Shipping Conditions

Wet Ice

Product Datasheet

Anti-FEM1B (ARP53703_P050-FITC) antibody

Protein Length

627

NCBI Gene Symbol

FEM1B

NCBI GB Accession Number

FEM1B

Host or Source

Rabbit

Protein Name

Protein fem-1 homolog B

Nucleotide Accession Number

NM_015322

Peptide Sequence

DKSTTGVSEILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH

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