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FEM1B Antibody - C-terminal region : Biotin (ARP53703_P050-Biotin)

Selected Variant

ARP53703_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Fem-1 homolog b (C. elegans)

Gene Aliases

F1AA, F1A-ALPHA, FEM1-beta

Gene ID

10116

Swiss Prot

Q9UK73

Accession Number

NP_056137

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FEM1B

Target

FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. FEM1B also involved in glucose homeostasis in pancreatic islet.

Partner Proteins

GLI1; HIF1AN; NKX3-1; fem-2; Ppm1f; UBC; RBX1; CUL2; TCEB2; TCEB1; Tnfrsf1a; Fem1b; Fas; Casp3; COPS4; RAD9A; CHEK1; DCUN1D1; COPS5; COPS6; CUL5; NEDD8; KIAA0319; GNB2L1; APAF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

FEM1B is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Kamura, T., (2004) Genes Dev. 18 (24), 3055-3065

Shipping Conditions

Wet Ice

Protein Length

627

NCBI Gene Symbol

FEM1B

NCBI GB Accession Number

FEM1B

Host or Source

Rabbit

Protein Name

Protein fem-1 homolog B

Nucleotide Accession Number

NM_015322

Peptide Sequence

DKSTTGVSEILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH

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