STAG3 Antibody - middle region : Biotin (ARP53683_P050-Biotin)
Selected Variant
ARP53683_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Stromal antigen 3
Gene ID
10734
Swiss Prot
Q9UJ98
Accession Number
NP_036579
Host
Rabbit
Reactivity
Human, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human STAG3
Target
STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
Partner Proteins
SMC3; SMC1A
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
STAG3 is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Human: 100%; Zebrafish: 83%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
135kDa
References & Citations
Barber, T.D., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (9), 3443-3448
Shipping Conditions
Wet Ice
Protein Length
1225
NCBI Gene Symbol
STAG3
NCBI GB Accession Number
STAG3
Host or Source
Rabbit
Protein Name
Cohesin subunit SA-3
Nucleotide Accession Number
NM_012447
Peptide Sequence
VPHQVILPALTLVYFSILWTLTHISKSDASQKQLSSLRDRMVAFCELCQS
Subunit
SA-3
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