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CCT6B Antibody - N-terminal region : FITC (ARP53660_P050-FITC)

Selected Variant

ARP53660_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Chaperonin containing TCP1, subunit 6B (zeta 2)

Gene Aliases

Cctz2, CCTZ-2, TSA303, CCT-zeta-2, TCP-1-zeta-2

Gene ID

10693

Swiss Prot

Q92526

Accession Number

NP_006575

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CCT6B

Target

CCT6B is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Partner Proteins

UBC; FAM86B2; METTL18; METTL21B; PAXIP1; CCT5; CCT2; CCT4; CCT3; TCP1; EIF4B; UBASH3B; FBXW8; PPP2R2D; STRN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CCT6B is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Stirling, P.C., (2006) J. Biol. Chem. 281 (11), 7012-7021

Shipping Conditions

Wet Ice

Protein Length

530

NCBI Gene Symbol

CCT6B

NCBI GB Accession Number

CCT6B

Host or Source

Rabbit

Protein Name

T-complex protein 1 subunit zeta-2

Nucleotide Accession Number

NM_006584

Peptide Sequence

VARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKL

Subunit

Zeta-2

Price

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