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CCT6B Antibody - N-terminal region : Biotin (ARP53660_P050-Biotin)

Product Specifications

Gene Name

Chaperonin containing TCP1, subunit 6B (zeta 2)

Gene Aliases

Cctz2, CCTZ-2, TSA303, CCT-zeta-2, TCP-1-zeta-2

Gene ID

10693

Swiss Prot

Q92526

Accession Number

NP_006575

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CCT6B

Target

CCT6B is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Partner Proteins

UBC; FAM86B2; METTL18; METTL21B; PAXIP1; CCT5; CCT2; CCT4; CCT3; TCP1; EIF4B; UBASH3B; FBXW8; PPP2R2D; STRN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CCT6B is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Stirling, P.C., (2006) J. Biol. Chem. 281 (11), 7012-7021

Shipping Conditions

Wet Ice

Protein Length

530

NCBI Gene Symbol

CCT6B

NCBI GB Accession Number

CCT6B

Host or Source

Rabbit

Protein Name

T-complex protein 1 subunit zeta-2

Nucleotide Accession Number

NM_006584

Peptide Sequence

VARTSLQTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKL

Subunit

Zeta-2

Frequently Asked Questions

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