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TUBA3C Antibody - N-terminal region : Biotin (ARP53650_P050-Biotin)

Selected Variant

ARP53650_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Tubulin, alpha 3c

Gene Aliases

TUBA2, bA408E5.3

Gene ID

7278

Swiss Prot

Q13748

Accession Number

NP_005992

Host

Rabbit

Reactivity

Human, Mouse, Rat, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TUBA3C

Target

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome.Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

CEP70; UBC; MDM2; CD81; K3; UBL4A; DYNLT1; TSGA10; CUL3; ARRB2; ARRB1; VHL; YWHAQ; DYRK2; YWHAZ; YWHAG; YWHAB; PPP4C; PFDN5; GRM7; NMI; PXN; SIAH1; DYNLL1; TUBG1; MYC; FYN; FBL

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TUBA3C is supported by BioGPS gene expression data to be expressed in HeLa, Jurkat

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Jin, J., (2004) Curr. Biol. 14 (16), 1436-1450

Shipping Conditions

Wet Ice

Protein Length

450

NCBI Gene Symbol

TUBA3C

NCBI GB Accession Number

TUBA3C

Host or Source

Rabbit

Protein Name

Tubulin alpha-3C/D chain

Nucleotide Accession Number

NM_006001

Peptide Sequence

VDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDL

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