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CDKN3 Antibody - C-terminal region : Biotin (ARP53629_P050-Biotin)

Product Specifications

Gene Name

Cyclin-dependent kinase inhibitor 3

Gene Aliases

KAP, CDI1, CIP2, KAP1

Gene ID

1033

Swiss Prot

Q16667

Accession Number

NP_005183

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CDKN3

Target

CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

CDK2; UBC; NCOA3; MS4A3; CDKN3; CDK3; CDC25A; CDK1; CEBPA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

References & Citations

Okamoto, K., (2006) Biochem. Biophys. Res. Commun. 351 (1), 216-222

Shipping Conditions

Wet Ice

Protein Length

212

NCBI Gene Symbol

CDKN3

NCBI GB Accession Number

CDKN3

Host or Source

Rabbit

Protein Name

Cyclin-dependent kinase inhibitor 3

Nucleotide Accession Number

NM_005192

Peptide Sequence

CKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCG

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