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DNALI1 Antibody - C-terminal region : HRP (ARP53612_P050-HRP)

Selected Variant

ARP53612_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Dynein, axonemal, light intermediate chain 1

Gene Aliases

P28, hp28, dJ423B22.5

Gene ID

7802

Swiss Prot

O14645

Accession Number

NP_003453

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human DNALI1

Target

DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS) . Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS) . Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.

Partner Proteins

SIAH1; PRMT6; APP; DNALI1; HTT; ABCF3; EPS8

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

References & Citations

Combs, J., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (40), 14883-14888

Shipping Conditions

Wet Ice

Protein Length

280

NCBI Gene Symbol

DNALI1

NCBI GB Accession Number

DNALI1

Host or Source

Rabbit

Protein Name

Axonemal dynein light intermediate polypeptide 1

Nucleotide Accession Number

NM_003462

Peptide Sequence

ALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVE

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