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ODF2 Antibody - N-terminal region : Biotin (ARP53603_P050-Biotin)

Product Specifications

Gene Name

Outer dense fiber of sperm tails 2

Gene Aliases

CT134, ODF84, ODF2/1, ODF2/2

Gene ID

4957

Swiss Prot

Q5BJF6-3

Accession Number

NP_002531

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ODF2

Target

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. ODF2 is one of the major outer dense fiber proteins.The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of this gene; however, not all isoforms and variants have been fully described.

Partner Proteins

UBC; MARK4; FBXO25; BRCA1; APP; SP1; ELAVL1; SVIL; ODF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

89kDa

References & Citations

Soung, N.K., (2006) Mol. Cell. Biol. 26 (22), 8316-8335

Shipping Conditions

Wet Ice

Protein Length

805

NCBI Gene Symbol

ODF2

NCBI GB Accession Number

ODF2

Host or Source

Rabbit

Protein Name

Outer dense fiber protein 2

Nucleotide Accession Number

NM_002540

Peptide Sequence

TCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQG

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