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ADAM2 Antibody - middle region : HRP (ARP53589_P050-HRP)

Product Specifications

Gene Name

ADAM metallopeptidase domain 2

Gene Aliases

CT15, FTNB, PH30, CRYN1, CRYN2, PH-30b, PH30-beta

Gene ID

2515

Swiss Prot

Q99965

Accession Number

NP_001455

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ADAM2

Target

ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.

Partner Proteins

DNM1; CRYAB; CLGN; CD9

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

81kDa

References & Citations

Eto, K., (2002) J. Biol. Chem. 277 (20), 17804-17810

Shipping Conditions

Wet Ice

Protein Length

735

NCBI Gene Symbol

ADAM2

NCBI GB Accession Number

ADAM2

Host or Source

Rabbit

Protein Name

Disintegrin and metalloproteinase domain-containing protein 2

Nucleotide Accession Number

NM_001464

Peptide Sequence

PHDVAFLLVYREKSNYVGATFQGKMCDANYAGGVVLHPRTISLESLAVIL

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