AURKC Antibody - middle region : Biotin (ARP53575_P050-Biotin)

Product Specifications

Gene Name

Aurora kinase C

Gene Aliases

AIE2, AIK3, ARK3, AurC, SPGF5, STK13, HEL-S-90, aurora-C

Gene ID

6795

Swiss Prot

Q9UQB9

Accession Number

NP_001015878

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AURKC

Target

AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Partner Proteins

SRPK1; AURKB; HIST1H3A; INCENP; BIRC5; TACC2; UBC; HSP90AA1; BRCA1; LNX1; NEDD4L; NEDD4; CENPA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Goat: 79%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Lim, J., (2007) Cell Cycle 6 (20), 2579-2580

Shipping Conditions

Wet Ice

Protein Length

309

NCBI Gene Symbol

AURKC

NCBI GB Accession Number

AURKC

Host or Source

Rabbit

Protein Name

Aurora kinase C

Nucleotide Accession Number

NM_001015878

Peptide Sequence

TYDEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPL

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